GRANIX is a prescription medication given to people with certain types of cancer
(nonmyeloid malignancies) who are receiving chemotherapy that affects the bone marrow
to decrease the length of time that certain white blood cells (neutrophils) are
very low (severe neutropenia).
It is not known if GRANIX is safe and effective in children under 18 years of age.
What should I tell my doctor before I receive GRANIX?
Before you take GRANIX, tell your doctor if you have sickle cell anemia or other
blood problems, plan to have bone scans or tests, are allergic to filgrastim (NEUPOGEN®) or pegfilgrastim (Neulasta®), or have any other medical
conditions. It is not known if GRANIX will harm an unborn baby or passes into breast
milk; tell your doctor if you are pregnant or plan to become pregnant, or if you
are breastfeeding or plan to breastfeed.
What are the possible side effects of GRANIX?
- Spleen rupture, which can cause death. Call
your doctor right away if you have pain in your left upper stomach area or left
shoulder area while taking GRANIX. This pain could mean your spleen is enlarged
- A serious lung problem called Acute Respiratory Distress
Syndrome (ARDS). Get medical help right away if you have any of these
symptoms of Acute Respiratory Distress Syndrome (ARDS): fever, shortness of breath,
- Serious Allergic Reactions. If you have a serious
allergic reaction during a GRANIX injection, stop giving yourself the injection
and call your doctor right away. Symptoms of serious allergic reaction can occur
during or after your injection and include: a rash over the whole body, shortness of breath,
trouble breathing (wheezing), dizziness, swelling around the mouth or eyes, fast
heart rate, sweating.
- Severe Sickle Cell Crisis in people with sickle cell disease.
If you have sickle cell disease, talk to your doctor about the risks of taking GRANIX.
The most common side effect of GRANIX is bone pain.
Tell your doctor about any side effect that bothers you or that does not go away.
These are not all the possible side effects of GRANIX. For a complete list, ask
your doctor or pharmacist.
Click here to access the
Full Prescribing Information for GRANIX.
You are encouraged to report any side effects of prescription drugs to the FDA.
fda.gov/medwatch, or call 1-800-FDA-1088.